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Intraindividual Comparison of Contrast Media Concentrations for Combined Abdominal and Thoracic MDCT

Florian F. Behrendt1, Andreas H. Mahnken1, Sven Stanzel2, Peter Seidensticker3, Edgar Jost4, Rolf W. Günther1 and Georg Mühlenbruch1

1 Department of Diagnostic Radiology, University Hospital RWTH Aachen, Pauwelsstraße 30, 52057 Aachen, Germany.
2 Institute of Medical Statistics, University Hospital RWTH Aachen, Aachen, Germany.
3 Bayer Schering Pharma, Berlin, Germany.
4 Medical Clinic IV, University Hospital RWTH Aachen, Aachen, Germany.


Figure 1
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Fig. 1 Contrast enhancement in chest. Graph shows comparison of contrast enhancement in right ventricle, pulmonary trunk, left ventricle, and descending thoracic aorta between 370 mg I/mL (white) and 300 mg I/mL (gray) protocols. Bars represent mean CT attenuation ± 1 SD. Intraindividual mean attenuation values are statistically significantly higher for 300 mg I/mL protocol than 370 mg I/mL protocol at all anatomic sites with exception of left ventricle.

 

Figure 2
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Fig. 2A 77-year-old man with lymphoma. MDCT scans of chest obtained with contrast media containing 370 mg I/mL (A) and 300 mg I/mL (B) show examples of region of interest measurements in pulmonary trunk. Mean contrast enhancement was statistically significantly higher for 300 mg I/mL than for 370 mg I/mL at all measured anatomic sites.

 

Figure 3
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Fig. 2B 77-year-old man with lymphoma. MDCT scans of chest obtained with contrast media containing 370 mg I/mL (A) and 300 mg I/mL (B) show examples of region of interest measurements in pulmonary trunk. Mean contrast enhancement was statistically significantly higher for 300 mg I/mL than for 370 mg I/mL at all measured anatomic sites.

 

Figure 4
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Fig. 3 Contrast enhancement in abdomen. Graph shows comparison of contrast enhancement in descending abdominal aorta, inferior vena cava, portal vein, and liver for 370 mg I/mL (white) and 300 mg I/mL (gray) protocols. Bars represent mean attenuation ± 1 SD. No statistically significant differences in intraindividual mean attenuation values were detected between two protocols at any measured anatomic site.

 

Figure 5
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Fig. 4A 70-year-old man with lymphoma. MDCT scans of abdomen obtained during portal venous phase with contrast media containing 370 mg I/mL (A) and 300 mg I/mL (B) show example of region of interest measurement in liver parenchyma. There was no statistically significant difference between protocols at any anatomic site.

 

Figure 6
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Fig. 4B 70-year-old man with lymphoma. MDCT scans of abdomen obtained during portal venous phase with contrast media containing 370 mg I/mL (A) and 300 mg I/mL (B) show example of region of interest measurement in liver parenchyma. There was no statistically significant difference between protocols at any anatomic site.

 

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