Intraindividual Comparison of Contrast Media Concentrations for Combined Abdominal and Thoracic MDCT
Florian F. Behrendt1,
Andreas H. Mahnken1,
Sven Stanzel2,
Peter Seidensticker3,
Edgar Jost4,
Rolf W. Günther1 and
Georg Mühlenbruch1
1 Department of Diagnostic Radiology, University Hospital RWTH Aachen,
Pauwelsstraße 30, 52057 Aachen, Germany.
2 Institute of Medical Statistics, University Hospital RWTH Aachen, Aachen,
Germany.
3 Bayer Schering Pharma, Berlin, Germany.
4 Medical Clinic IV, University Hospital RWTH Aachen, Aachen, Germany.

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Fig. 1 —Contrast enhancement in chest. Graph shows comparison of
contrast enhancement in right ventricle, pulmonary trunk, left ventricle, and
descending thoracic aorta between 370 mg I/mL (white) and 300 mg I/mL
(gray) protocols. Bars represent mean CT attenuation ± 1 SD.
Intraindividual mean attenuation values are statistically significantly higher
for 300 mg I/mL protocol than 370 mg I/mL protocol at all anatomic sites with
exception of left ventricle.
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Fig. 2A —77-year-old man with lymphoma. MDCT scans of chest obtained
with contrast media containing 370 mg I/mL (A) and 300 mg I/mL
(B) show examples of region of interest measurements in pulmonary
trunk. Mean contrast enhancement was statistically significantly higher for
300 mg I/mL than for 370 mg I/mL at all measured anatomic sites.
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Fig. 2B —77-year-old man with lymphoma. MDCT scans of chest obtained
with contrast media containing 370 mg I/mL (A) and 300 mg I/mL
(B) show examples of region of interest measurements in pulmonary
trunk. Mean contrast enhancement was statistically significantly higher for
300 mg I/mL than for 370 mg I/mL at all measured anatomic sites.
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Fig. 3 —Contrast enhancement in abdomen. Graph shows comparison of
contrast enhancement in descending abdominal aorta, inferior vena cava, portal
vein, and liver for 370 mg I/mL (white) and 300 mg I/mL
(gray) protocols. Bars represent mean attenuation ± 1 SD. No
statistically significant differences in intraindividual mean attenuation
values were detected between two protocols at any measured anatomic site.
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Fig. 4A —70-year-old man with lymphoma. MDCT scans of abdomen obtained
during portal venous phase with contrast media containing 370 mg I/mL
(A) and 300 mg I/mL (B) show example of region of interest
measurement in liver parenchyma. There was no statistically significant
difference between protocols at any anatomic site.
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Fig. 4B —70-year-old man with lymphoma. MDCT scans of abdomen obtained
during portal venous phase with contrast media containing 370 mg I/mL
(A) and 300 mg I/mL (B) show example of region of interest
measurement in liver parenchyma. There was no statistically significant
difference between protocols at any anatomic site.
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Copyright © 2008 by the American Roentgen Ray Society.