HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Abstract Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Citation Map Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via HighWire Citing Articles via Google Scholar Google Scholar Articles by Nagao, M. Articles by Uemura, M. Search for Related Content PubMed PubMed Citation Articles by Nagao, M. Articles by Uemura, M. Social Bookmarking                      What's this? Hotlight (NEW!) What's Hotlight?

Quantification of Myocardial Perfusion by Contrast-Enhanced 64-MDCT: Characterization of Ischemic Myocardium

¹ Department of Radiology, Prefectural Ehime Imabari Hospital, Ishii-cho 4-5-5, Imabari-city, Ehime 794-0006, Japan.
² Department of Cardiology, Prefectural Ehime Imabari Hospital, Ehime, Japan.
³ Department of Radiology, Ehime University Medical School, Ehime, Japan.
⁴ Department of Medical Engineering, Division of Allied Health Sciences, Osaka University Medical School, Osaka, Japan.

View larger version (149K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1 —Crescent-shaped regions of interest (ROIs) in subendocardium of 55-year-old woman who was a healthy control subject were placed manually on 2D short-axis and vertical long-axis cardiac images, according to American Heart Association classification. We measured myocardial thickness for 17 segments at systole and diastole and calculated mean values for them. Thickness of ROI was defined as half of mean value at systole and diastole.

View larger version (18K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2 —Diagram shows control data for systolic myocardial perfusion (top row), diastolic myocardial perfusion (middle row), and difference between systolic and diastolic myocardial perfusion (bottom row). Numbers indicate mean attenuation value in Hounsfield units as percentage for each segment.

View larger version (8K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3 —Diagram shows ischemic and nonischemic segments detected by stress/rest myocardial perfusion scintigraphy (MPS). Numbers indicate number of ischemic/nonischemic segments for each segment detected by stress/rest MPS.

View larger version (16K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4 —Diagram shows comparison of systolic myocardial perfusion between ischemia (upper row) and nonischemia (lower row). Numbers indicate mean attenuation value in Hounsfield units as percentage for each segment. Systolic perfusion for ischemia in shaded segments was significantly lower than that for nonischemia (segments 3, 6, 7, 9, 10, 12, 15, 16, p < 0.01; segments 1, 2, 5, 8, 13, 14, 17, p < 0.05).

View larger version (15K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 5 —Diagram shows comparison of diastolic myocardial perfusion between ischemia (upper row) and nonischemia (lower row). Numbers indicate mean attenuation value in Hounsfield units as percentage for each segment. Diastolic perfusion for nonischemia in shaded segments was significantly lower than that for ischemia (p < 0.05).

View larger version (16K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 6 —Diagram shows comparison of difference between systolic and diastolic myocardial perfusion between ischemia (upper row) and nonischemia (lower row). Numbers indicate mean attenuation value in Hounsfield units as percentage for each segment. Difference between systolic and diastolic myocardial perfusion for ischemia in shaded segments was significantly lower than that for nonischemia (segments 1, 5, 6, 7, 10, 12, 17, p < 0.001; segments 2, 3, 4, 9, 11, 13, 15, p < 0.01).

View larger version (105K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 7A —Myocardial perfusion scintigraphy (MPS) and CT images of 79-year-old woman with rest angina pectoris. Top row shows midventricular short-axis slices on stress/rest MPS; bottom row shows perfusion CT images at same slice positions. Stress MPS image on left shows hypoperfusion in anteroseptal wall (arrow); delayed image on right shows redistribution. Systolic perfusion CT image on left shows endocardial hypoperfusion in anteroseptal wall (arrowhead); diastolic image on right shows normal perfusion.

View larger version (57K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 7B —Myocardial perfusion scintigraphy (MPS) and CT images of 79-year-old woman with rest angina pectoris. Volume-rendered (left) and curved maximum-intensity-projection (right) images from coronary CT angiography show diffusely severe stenosis (arrowheads) with linear and nodular extrinsic calcifications at proximal and mid portions of left anterior descending branch.

View larger version (114K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 8A —Myocardial perfusion scintigraphy (MPS) and CT images of 53-year-old woman with effort angina pectoris. Top row shows long-axis slices on stress/rest MPS; bottom row shows perfusion CT images at same slice positions. Stress MPS image on left shows anterior hypoperfusion (arrow); delayed image on right shows redistribution. Systolic perfusion CT image on left shows endocardial anterior hypoperfusion (arrowhead); diastolic image on right shows normal perfusion.

View larger version (74K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 8B —Myocardial perfusion scintigraphy (MPS) and CT images of 53-year-old woman with effort angina pectoris. Volume-rendered (left) and curved maximum-intensity-projection (right) images from coronary CT angiography show mild stenosis at proximal portion of left anterior descending branch (arrowheads).

CiteULike

Complore

Connotea

Del.icio.us

Digg

Reddit

Technorati