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Hepatocellular Carcinoma in Liver Transplantation Candidates: Detection with Gadobenate Dimeglumine–Enhanced MRI

Seung Hong Choi1, Jeong Min Lee1, Nam C. Yu2, Kyung-Suk Suh3, Ja-June Jang4, Se Hyung Kim1 and Byung Ihn Choi1

1 Department of Radiology and Institute of Radiation Medicine, Seoul National University College of Medicine, Clinical Research Institute, Seoul National University Hospital, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
2 Department of Radiology, David Geffen School of Medicine at the University of California, Los Angeles, Los Angeles, CA.
3 Department of Surgery, Seoul National University Hospital, Seoul, Korea.
4 Department of Pathology, Seoul National University Hospital, Seoul, Korea.


Figure 1
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Fig. 1A 55-year-old man with macronodular cirrhosis and 1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Unenhanced axial T1-weighted volumetric interpolated breath-hold examination (VIBE) image (TR/TE, 3.6/1.7; flip angle, 12°) shows no liver lesion.

 

Figure 2
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Fig. 1B 55-year-old man with macronodular cirrhosis and 1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Hepatic arterial phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows enhancing nodule (arrow) in liver segment 7.

 

Figure 3
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Fig. 1C 55-year-old man with macronodular cirrhosis and 1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Portal venous phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows no liver lesion.

 

Figure 4
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Fig. 1D 55-year-old man with macronodular cirrhosis and 1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Delayed axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) obtained 1 hour after gadobenate dimeglumine administration shows no liver lesion.

 

Figure 5
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Fig. 1E 55-year-old man with macronodular cirrhosis and 1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Photomicrograph of sagittal section of pathologic specimen shows 1.3-cm-diameter hepatocellular carcinoma nodule (arrow) in segment 7.

 

Figure 6
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Fig. 2A 47-year-old man with macronodular cirrhosis. Unenhanced axial T1-weighted volumetric interpolated breath-hold examination (VIBE) image (TR/TE, 3.6/1.7; flip angle, 12°) shows no liver lesion.

 

Figure 7
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Fig. 2B 47-year-old man with macronodular cirrhosis. Hepatic artery phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows enhancing 9-mm-diameter lesion (arrow) in liver segment 5. No nodule was identified at pathologic examination. Lesion was considered nonneoplastic arterial hypervascular lesion.

 

Figure 8
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Fig. 2C 47-year-old man with macronodular cirrhosis. Portal venous phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows subtle enhancing lesion (arrow) in liver segment 5.

 

Figure 9
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Fig. 3A 38-year-old man with macronodular cirrhosis and 8-mm-diameter dysplastic nodule in liver segment 4. Unenhanced axial T1-weighted volumetric interpolated breath-hold examination (VIBE) image (TR/TE, 3.6/1.7; flip angle, 12°) shows no liver lesion.

 

Figure 10
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Fig. 3B 38-year-old man with macronodular cirrhosis and 8-mm-diameter dysplastic nodule in liver segment 4. Hepatic arterial phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows enhancing mass (arrow) in liver segment 4.

 

Figure 11
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Fig. 3C 38-year-old man with macronodular cirrhosis and 8-mm-diameter dysplastic nodule in liver segment 4. Portal venous phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle, 12°) shows no liver lesion.

 

Figure 12
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Fig. 3D 38-year-old man with macronodular cirrhosis and 8-mm-diameter dysplastic nodule in liver segment 4. Photomicrograph of sagittal section of pathologic specimen shows 8-mm-diameter dysplastic nodule (arrow) in segment 4.

 

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