Hepatocellular Carcinoma in Liver Transplantation Candidates: Detection with Gadobenate Dimeglumine–Enhanced MRI
Seung Hong Choi1,
Jeong Min Lee1,
Nam C. Yu2,
Kyung-Suk Suh3,
Ja-June Jang4,
Se Hyung Kim1 and
Byung Ihn Choi1
1 Department of Radiology and Institute of Radiation Medicine, Seoul National
University College of Medicine, Clinical Research Institute, Seoul National
University Hospital, 28, Yongon-dong, Chongno-gu, Seoul, 110-744, Korea.
2 Department of Radiology, David Geffen School of Medicine at the University of
California, Los Angeles, Los Angeles, CA.
3 Department of Surgery, Seoul National University Hospital, Seoul, Korea.
4 Department of Pathology, Seoul National University Hospital, Seoul,
Korea.

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Fig. 1A —55-year-old man with macronodular cirrhosis and
1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Unenhanced axial
T1-weighted volumetric interpolated breath-hold examination (VIBE) image
(TR/TE, 3.6/1.7; flip angle, 12°) shows no liver lesion.
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Fig. 1B —55-year-old man with macronodular cirrhosis and
1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Hepatic arterial
phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image
(3.6/1.7; flip angle, 12°) shows enhancing nodule (arrow) in
liver segment 7.
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Fig. 1C —55-year-old man with macronodular cirrhosis and
1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Portal venous
phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image
(3.6/1.7; flip angle, 12°) shows no liver lesion.
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Fig. 1D —55-year-old man with macronodular cirrhosis and
1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Delayed axial
T1-weighted VIBE image (3.6/1.7; flip angle, 12°) obtained 1 hour after
gadobenate dimeglumine administration shows no liver lesion.
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Fig. 1E —55-year-old man with macronodular cirrhosis and
1.3-cm-diameter hepatocellular carcinoma in liver segment 7. Photomicrograph
of sagittal section of pathologic specimen shows 1.3-cm-diameter
hepatocellular carcinoma nodule (arrow) in segment 7.
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Fig. 2A —47-year-old man with macronodular cirrhosis. Unenhanced axial
T1-weighted volumetric interpolated breath-hold examination (VIBE) image
(TR/TE, 3.6/1.7; flip angle, 12°) shows no liver lesion.
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Fig. 2B —47-year-old man with macronodular cirrhosis. Hepatic artery
phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image
(3.6/1.7; flip angle, 12°) shows enhancing 9-mm-diameter lesion
(arrow) in liver segment 5. No nodule was identified at pathologic
examination. Lesion was considered nonneoplastic arterial hypervascular
lesion.
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Fig. 2C —47-year-old man with macronodular cirrhosis. Portal venous
phase gadobenate dimeglumine–enhanced axial T1-weighted VIBE image
(3.6/1.7; flip angle, 12°) shows subtle enhancing lesion (arrow)
in liver segment 5.
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Fig. 3A —38-year-old man with macronodular cirrhosis and 8-mm-diameter
dysplastic nodule in liver segment 4. Unenhanced axial T1-weighted volumetric
interpolated breath-hold examination (VIBE) image (TR/TE, 3.6/1.7; flip angle,
12°) shows no liver lesion.
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Fig. 3B —38-year-old man with macronodular cirrhosis and 8-mm-diameter
dysplastic nodule in liver segment 4. Hepatic arterial phase gadobenate
dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle,
12°) shows enhancing mass (arrow) in liver segment 4.
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Fig. 3C —38-year-old man with macronodular cirrhosis and 8-mm-diameter
dysplastic nodule in liver segment 4. Portal venous phase gadobenate
dimeglumine–enhanced axial T1-weighted VIBE image (3.6/1.7; flip angle,
12°) shows no liver lesion.
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Fig. 3D —38-year-old man with macronodular cirrhosis and 8-mm-diameter
dysplastic nodule in liver segment 4. Photomicrograph of sagittal section of
pathologic specimen shows 8-mm-diameter dysplastic nodule (arrow) in
segment 4.
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