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AJR Teaching File: Symmetric Demyelination

Nanda Venkatanarasimha1, William Mukonoweshuro and Jonathon Jones

1 All authors: Department of Radiology, Derriford Hospital, Level 6, Derriford Rd., Plymouth PL6 8DH, United Kingdom.


Figure 1
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  		Fig. 1A —40-year-old man with chronic alcohol abuse and acute onset walking difficulty, mild dysarthria, and blurring of vision. Unenhanced CT scan of head shows well-defined low-density focus in central pons.

 

Figure 2
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  		Fig. 1B —40-year-old man with chronic alcohol abuse and acute onset walking difficulty, mild dysarthria, and blurring of vision. Cranial T2-weighted MR image (TR/TE, 4,480/99) shows triangular area of high signal intensity in central pons and sparing of tegmentum and ventrolateral pons.

 

Figure 3
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  		Fig. 1C —40-year-old man with chronic alcohol abuse and acute onset walking difficulty, mild dysarthria, and blurring of vision. Axial fluid-attenuated inversion recovery image (8,630/111) shows trident-shaped pontine high-signal-intensity abnormality.

 

Figure 4
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  		Fig. 1D —40-year-old man with chronic alcohol abuse and acute onset walking difficulty, mild dysarthria, and blurring of vision. Axial T1-weighted gadolinium-enhanced image (533/8.1) shows triangular central pontine hypointensity with no enhancement.

 

Figure 5
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  		Fig. 1E —40-year-old man with chronic alcohol abuse and acute onset walking difficulty, mild dysarthria, and blurring of vision. Coronal T1-weighted gadolinium-enhanced image (553/8.1) shows nonenhancing central pontine low-signal abnormality.

 

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