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Dual-Time-Point ¹⁸F-FDG PET/CT Versus Dynamic Breast MRI of Suspicious Breast Lesions

¹ Dipartimento di Scienze Biomorfologiche e Funzionali, Università degli Studi di Napoli Federico II, Via Posillipo 196, 80123, Naples, Italy.
² National Research Council Napoli, Institute of Bio-structure and Bio-imaging, SDN Foundation, Naples, Italy.
³ Dipartimento di Chirurgia, Università degli Studi di Napoli Federico II, Naples, Italy.

View larger version (12K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1 —Graph shows changes in standard uptake values (SUV) between time points 1 and 2 in malignant lesions (n = 45). Student's t test for results shows p < 0.04.

View larger version (6K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2 —Graph shows changes in standard uptake values (SUV) between time points 1 and 2 in benign lesions (n = 10). Student's t test for results shows p < 0.01.

View larger version (100K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3A —55-year-old woman with ductal infiltrating adenocarcinoma measuring 15 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (103K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3B —55-year-old woman with ductal infiltrating adenocarcinoma measuring 15 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (74K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3C —55-year-old woman with ductal infiltrating adenocarcinoma measuring 15 mm in maximum transverse diameter. Subtracted contrast-enhanced T1-weighted axial MR image shows focal area of intense 18F-FDG uptake and marked gadolinium enhancement in inferior inner quadrant of left breast.

View larger version (12K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 3D —55-year-old woman with ductal infiltrating adenocarcinoma measuring 15 mm in maximum transverse diameter. Graph shows signal intensity curve obtained from dynamic contrast-enhanced MRI.

View larger version (81K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4A —32-year-old woman with ductal infiltrating adenocarcinoma measuring 18 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (90K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4B —32-year-old woman with ductal infiltrating adenocarcinoma measuring 18 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (86K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4C —32-year-old woman with ductal infiltrating adenocarcinoma measuring 18 mm in maximum transverse diameter. Subtracted contrast-enhanced T1-weighted axial MR image shows focal area of intense 18F-FDG uptake and marked gadolinium enhancement in superior inner quadrant of right breast.

View larger version (13K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 4D —32-year-old woman with ductal infiltrating adenocarcinoma measuring 18 mm in maximum transverse diameter. Graph shows signal intensity curve obtained from dynamic contrast-enhanced MRI.

View larger version (110K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 5A —42-year-old woman with lobular infiltrating adenocarcinoma of 16 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (109K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 5B —42-year-old woman with lobular infiltrating adenocarcinoma of 16 mm in maximum transverse diameter. Axial fused PET/CT images obtained with patient in prone position at time point 1 (A) and time point 2 (B) show corresponding standard uptake values.

View larger version (60K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 5C —42-year-old woman with lobular infiltrating adenocarcinoma of 16 mm in maximum transverse diameter. Subtracted contrast-enhanced T1-weighted axial MR image shows focal area of intense 18F-FDG uptake and marked gadolinium enhancement in inferior outer quadrant of left breast.

View larger version (8K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 5D —42-year-old woman with lobular infiltrating adenocarcinoma of 16 mm in maximum transverse diameter. Graph shows signal intensity curve obtained from dynamic contrast-enhanced MRI.

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