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Use of N-Butyl Cyanoacrylate in Implantation of a Port-Catheter System for Hepatic Arterial Infusion Chemotherapy with the Fixed-Catheter-Tip Method: Is It Necessary?

Takuji Yamagami1, Koshi Terayama, Rika Yoshimatsu, Tomohiro Matsumoto, Hiroshi Miura and Tsunehiko Nishimura

1 All authors: Department of Radiology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-chyo, Kawaramachi-Hirokoji, Kamigyo, Kyoto 602-8566, Japan.


Figure 1
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Fig. 1A 69-year-old man with liver metastasis from rectum in whom port-catheter was placed with fixed-catheter-tip method without use of N-butyl cyanoacrylate and Lipiodol (iodized oil, Laboratoire Guerbet) mixture. Arteriography performed during infusion of contrast agent via port just after implantation shows that indwelling port-catheter system is precisely implanted. All hepatic artery branches are shown. Distal tip of catheter is fixed to gastroduodenal artery with microcoils (thick arrows), and side hole opens into common hepatic artery (arrowhead). Note that right gastric artery is embolized with microcoils (thin arrows).

 

Figure 2
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Fig. 1B 69-year-old man with liver metastasis from rectum in whom port-catheter was placed with fixed-catheter-tip method without use of N-butyl cyanoacrylate and Lipiodol (iodized oil, Laboratoire Guerbet) mixture. Arteriography via port performed 196 days after implantation of port-catheter system shows that side hole has moved to celiac artery (arrowhead).

 

Figure 3
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Fig. 2A 67-year-old woman with hepatocellular carcinoma in whom port-catheter was placed with fixed-catheter-tip method using mixture of N-butyl cyanoacrylate (NBCA) and Lipiodol (iodized oil, Laboratoire Guerbet) (patient 6 in Table 3). Arteriography during port-catheter implantation procedure shows that port-catheter is positioned with catheter tip fixed to gastroduodenal artery but that some of NBCA–Lipiodol mixture has migrated from gastroduodenal artery (large arrow) to proper hepatic artery (small arrows). Note that microcoils can be seen in replaced right hepatic artery (large arrowhead) originating from celiac artery and right gastric artery (small arrowhead), both of which were inserted as preparation before implantation of port-catheter system.

 

Figure 4
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Fig. 2B 67-year-old woman with hepatocellular carcinoma in whom port-catheter was placed with fixed-catheter-tip method using mixture of N-butyl cyanoacrylate (NBCA) and Lipiodol (iodized oil, Laboratoire Guerbet) (patient 6 in Table 3). Radiograph shows performance of percutaneous transluminal angioplasty for lesion of hepatic artery narrowing caused by migration of NBCA–Lipiodol mixture that was obtained immediately after migration during procedure for port-catheter implantation (arrow).

 

Figure 5
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Fig. 2C 67-year-old woman with hepatocellular carcinoma in whom port-catheter was placed with fixed-catheter-tip method using mixture of N-butyl cyanoacrylate (NBCA) and Lipiodol (iodized oil, Laboratoire Guerbet) (patient 6 in Table 3). Arteriography via port performed just after percutaneous transluminal angioplasty shows that narrowed lesion was sufficiently recanalized and all hepatic artery branches are revealed. Note microcoil (arrow) used for embolization of accessory left gastric artery.

 

Figure 6
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Fig. 2D 67-year-old woman with hepatocellular carcinoma in whom port-catheter was placed with fixed-catheter-tip method using mixture of N-butyl cyanoacrylate (NBCA) and Lipiodol (iodized oil, Laboratoire Guerbet) (patient 6 in Table 3). Arteriography via port performed 76 days after implantation of port-catheter system reveals severe stenosis of proper hepatic artery.

 

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