Aortic and Hepatic Contrast Enhancement with Abdominal 64-MDCT in Pediatric Patients: Effect of Body Weight and Iodine Dose
Kyongtae T. Bae1,
Amisha J. Shah1,
Sherry S. Shang1,2,
Jin Hong Wang1,
Samuel Chang1,
Masayuki Kanematsu3 and
Charles F. Hildebolt4
1 Department of Radiology, University of Pittsburgh School of Medicine, 3362
Fifth Ave., Pittsburgh, PA 15213.
2 Department of Radiology, Hahnemann University Hospital, Drexel University
College of Medicine, Philadelphia, PA.
3 Department of Radiology, Gifu University School of Medicine, Gifu,
Japan.
4 Mallinckrodt Institute of Radiology, Washington University School of Medicine,
St. Louis, MO.
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Fig. 1A —Transverse CT images in patients with three different body
sizes (small, medium, and large) in whom different degrees of aortic and
hepatic attenuations were seen. (Image display window width, 300 HU; center,
30 HU.) 6-year-old girl who weighed 20 kg (small body size) and received 40 mL
of contrast medium (contrast medium iodine mass per body weight index, 0.70)
had 195 HU of aortic and 134.5 HU of hepatic attenuation.
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Fig. 1B —Transverse CT images in patients with three different body
sizes (small, medium, and large) in whom different degrees of aortic and
hepatic attenuations were seen. (Image display window width, 300 HU; center,
30 HU.) 12-year-old boy who weighed 50 kg (medium body size) and received 80
mL of contrast medium (contrast medium iodine mass per body weight index,
0.56) had 131 HU of aortic and 111 HU of hepatic attenuation.
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Fig. 1C —Transverse CT images in patients with three different body
sizes (small, medium, and large) in whom different degrees of aortic and
hepatic attenuations were seen. (Image display window width, 300 HU; center,
30 HU.) 17-year-old boy who weighed 75 kg (large body size) and received 80 mL
of contrast medium (contrast medium iodine mass per body weight index, 0.37)
had 104 HU of aortic and 72 HU of hepatic attenuation.
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Fig. 2A —Graphs of attenuation against contrast medium iodine mass per
body weight index with 95% CI fit to regression lines. Plots of aortic
(A) and hepatic (B) attenuation against contrast medium iodine
mass per body weight index show moderately strong correlations existed between
index and aortic (Spearman's rho [rs] = 0.60 [95% CI,
0.45–0.72], p < 0.001) and hepatic (rs =
0.60 [0.42–0.70], p < 0.001) attenuations. Regression
formulae are aortic attenuation = 58.4 + 176.3 x contrast medium iodine
mass per body weight index (p < 0.001), and hepatic attenuation =
58.7 + 108.5 x contrast medium iodine mass per body weight index
(p < 0.001).
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Fig. 2B —Graphs of attenuation against contrast medium iodine mass per
body weight index with 95% CI fit to regression lines. Plots of aortic
(A) and hepatic (B) attenuation against contrast medium iodine
mass per body weight index show moderately strong correlations existed between
index and aortic (Spearman's rho [rs] = 0.60 [95% CI,
0.45–0.72], p < 0.001) and hepatic (rs =
0.60 [0.42–0.70], p < 0.001) attenuations. Regression
formulae are aortic attenuation = 58.4 + 176.3 x contrast medium iodine
mass per body weight index (p < 0.001), and hepatic attenuation =
58.7 + 108.5 x contrast medium iodine mass per body weight index
(p < 0.001).
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Copyright © 2008 by the American Roentgen Ray Society.
