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AJR 2000; 175:898
© American Roentgen Ray Society


Sonography Case of the Day

Case 1

Thyroid Hemiagenesis with Adenoma

Kuldeep Vaswani, Kenneth M. Vitellas and William F. Bennett

Sonography (Fig. 1A) reveals absence of the left thyroid lobe and enlargement of the right thyroid lobe, which contains a mixed echogenic nodule. The incidence of a thyroid nodule is 4-8% by palpation and approximately 50% at autopsy or sonography. Thyroid nodules are multiple in approximately 40% of patients and solitary in approximately 10% of patients. Adenomatous nodules predominate. Imaging studies cannot reliably distinguish between carcinoma and benign adenoma. Fine-needle aspiration is usually performed for diagnosis, with 60-90% diagnostic accuracy. Large needle core biopsies usually result in more complications and no significant increase in diagnostic accuracy.



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Fig. 1A. —70-year-old woman with multiple nodular densities in cervical region that are palpable on physical examination. Sonogram of neck shows no left thyroid lobe, consistent with congenital absence. Right lobe is enlarged, with mixed echogenic mass (arrows). Fine-needle aspiration was consistent with adenoma.

 

Thyroid-related anomalies usually result from abnormal descent of the thyroglossal duct. Low or arrested descent can result in ectopic thyroid tissue [1]. Obliteration can result in cysts, sinus tracts, and absence. Thyroid agenesis is uncommon. Hemiagenesis is also uncommon; however, when it does occur, it often involves the left lobe. This may result in dysfunction or hypertrophy of the remaining lobe [2]. At times, a pyramidal lobe can also be seen [3].

Thyroid nodules are incidental findings in 4-8% of adults. Most of these are benign adenomas, follicular nodules, or colloid cysts. They can hemorrhage and become infected. Malignancy is always a consideration. Patients with a history of radiation who are younger than 20 or older than 60 years are at increased risk for malignancy. Metastatic disease to the thyroid is less common, usually originating from the breast, lung, renal primary cancer, or melanoma. Imaging studies cannot reliably distinguish between benign and malignant processes [4, 5].

Lymphoma is not the correct diagnosis because no other lymph nodes or masses were appreciated on examination. A single reactive lymph node could still be in the differential diagnosis. However, the sonogram (Fig. 1A) shows a well-circumscribed mass containing mixed echogenic nodule, corresponding to the right lobe of the thyroid.

Carotid artery aneurysm is incorrect because the mass seen here is not originating from the carotid artery. Furthermore, no bruits were found on physical examination. CT performed several months before this examination (Fig. 1B) showed this mass to be originating from the right lobe of the thyroid.



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Fig. 1B. —70-year-old woman with multiple nodular densities in cervical region that are palpable on physical examination. CT scan obtained 9 months before sonogram shows absent left thryoid lobe and enlarged right thryoid lobe with small low-attenuation lesion (arrows). Patient denied any past surgical intervention.

 

References

  1. Murray-Carpenter BL, Merten DF. Radiographic manifestations of congenital anomalies affecting airways. Radiol Clin North Am 1991;29:219 -240[Medline]
  2. Vazquez E, Enriquez I, Castellote A, Lucaya J, Creixell S. US, CT and MR imaging of neck lesions in children. RadioGraphics 1995;15:105 -122[Abstract]
  3. Chiles C, Davis KW, Williams DW. Navigating the thoracic inlet. RadioGraphics 1999;19:1161 -1176[Abstract/Free Full Text]
  4. Harvey HK. Diagnosis and management of the thyroid nodule. Otolaryngol Clin North Am 1990;23:303 -307[Medline]
  5. Loevner LA. Imaging of the thyroid gland. Semin Ultrasound CT MR 1996;17:539 -562[Medline]

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This Article
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