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Fig. 3. —8-year-old boy with cerebral adrenoleukodystrophy. Axial T1-weighted MR image (TR/TE, 516/14) (left image) at level of lateral ventricles shows low signal intensity (prolonged T1 relaxation time) involving splenium of corpus callosum and deep white matter of both frontal and parietooccipital lobes. Axial T2-weighted MR image (3000/100) (center image) shows corresponding high signal intensity (prolonged T2 relaxation time) in involved regions. Axial fluid-attenuated inversion recovery MR image (TR/TI/TE, 6000/2000/53) (right image) shows low signal intensity in center (asterisks) and high signal intensity in periphery (arrowheads) of white matter lesion in both parietooccipital lobes. The low signal intensity in center of lesion is presumably a result of more severely damaged white matter and greater prolongation of T1 relaxation time.

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