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Fig. 3. —Drawing illustrates sacromeric protein mutations, which cause hypertrophic cardiomyopathy. Sarcomere (A) is basic unit of myocardial contraction. Magnified view of region shown in inset (B) depicts individual protein components of thick and thin filaments of sarcomere. Morphology and prognosis (C) of various hypertrophic cardiomyopathies due to mutations of specific sarcomeric contractile proteins are shown. LV = left ventricle.

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