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Fig. 5B. —Pathologic difference was consistent throughout primary biliary cirrhosis cohort in regard to visibility of MR imaging periportal halo sign. Photomicrographs of liver tissue from 41-year-old woman with primary biliary cirrhosis with positive MR finding for periportal halo sign (A) and from 37-year-old woman with primary biliary cirrhosis with negative MR finding for periportal halo sign (B). Stellate areas of hepatocellular parenchymal extinction (arrows, A) around portal triads can be seen in A but not in B. Larger and more variably sized regenerating nodules encircle fibrotic portal triads in patient with MR finding for periportal halo sign (A). Scale = 1-cm section. (H and E, x20)

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