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Fig. 3D. —50-year-old woman, a nonsmoker, with well-differentiated adenocarcinoma (16 x 18 mm) (type C of Noguchi et al. [11]) in apical segment of upper lobe of right lung. Photomicrograph of histology specimen with elastica—van Gieson staining of tumor shows in increased amount of elastic fibers with disrupted framework caused by tumor invasion in central zone (C). (x2)

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