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AJR 2001; 176:1446-1448
© American Roentgen Ray Society


Case Report

Detection of Encrusted Indwelling Ureteral Stents Using a Twinkling Artifact Revealed on Color Doppler Sonography

Hervé Trillaud1, Jean-Louis Pariente2, Abdelhack Rabie1 and Nicolas Grenier1

1 Service de Radiologie, Groupe Hospitalier Pellegrin, Place Amélie Raba-Léon, 33076 Bordeaux Cedex, France.
2 Service d'Urologie, Groupe Hospitalier Pellegrin, 33076 Bordeaux Cedex, France.

Received July 19, 2000; accepted after revision November 11, 2000.

 
Address correspondence to N. Grenier.


Introduction
Top
Introduction
Observations
Discussion
References
 
Indwelling ureteral stents are widely used in urology practice to relieve ureteral obstruction. Encrustation of both extremities of the stent is a frequent complication [1, 2]. Such encrustation may cause obstruction with hydroureter and hydronephrosis; this may complicate withdrawal of the stent and increase the risk of urothelial damage [1]. To avoid such a complication, the use of longterm stents with regular replacement is recommended [3, 4].

To date, diagnosis of encrustation of ureteral stents has been based only on unenhanced radiographs of the abdomen. Using color-flow Doppler sonography, a color artifact called the twinkling artifact has been described behind calcifications and, in particular, behind urinary stones [5]. This artifact, which results from complex physical mechanisms, is related to the irregularity of the surface of the calcifications [6]. It appears as a random color encoding behind the stones, in the region where shadowing would be expected on gray-scale images.

We present two cases of stent encrustation detected on color-flow Doppler sonography.


Observations
Top
Introduction
Observations
Discussion
References
 
First Patient
During her fifth month of pregnancy, a 33-year-old woman presented with ureterolithiasis of the right ureter requiring urologic treatment with stent placement. Three months later, Doppler sonography showed thickened extremities of the stent with a highly echogenic pattern and acoustic shadowing (Figs. 1A and 1B). With the color Doppler mode, a massive and intense color twinkling artifact appeared (Figs. 1C and 1D). Radiographs of the abdomen confirmed the large encrustation of both stent extremities (Figs. 1E and 1F). The stent was withdrawn 1 month later, after delivery. This procedure required the use of a pulsed-dye laser to free the encrusted stent. Chemical analysis of stone fragments showed calcium phosphate.



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Fig. 1A. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. B-mode sonograms of upper intrarenal (A) and lower intravesical (B) extremities of right ureteral stent show thickening of stent. Note highly echogenic pattern and acoustic shadowing.

 


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Fig. 1B. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. B-mode sonograms of upper intrarenal (A) and lower intravesical (B) extremities of right ureteral stent show thickening of stent. Note highly echogenic pattern and acoustic shadowing.

 


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Fig. 1C. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. Color Doppler sonograms reveal large twinkling artifact despite high color velocity scale.

 


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Fig. 1D. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. Color Doppler sonograms reveal large twinkling artifact despite high color velocity scale.

 


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Fig. 1E. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. Magnified unenhanced radiographs of upper (E) and lower (F) extremities of stent show gross encrustation.

 


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Fig. 1F. 33-year-old pregnant woman (8 months) with gross encrustation of ureteral stent. Magnified unenhanced radiographs of upper (E) and lower (F) extremities of stent show gross encrustation.

 

Second Patient
A 40-year-old woman underwent a right ureteral pure silicone stent placement for a ureterolithiasis of the lower ureter, requiring urologic treatment during her fourth month of pregnancy. Two months later she presented with hematuria without pain. Scans obtained with B-mode sonography of the bladder did not show any abnormality of the lower end of the stent. Its upper end could not be identified in the absence of dilatation of the upper cavities. On color Doppler sonography, a twinkling artifact was present at the lower intravesical end of the stent (Fig. 2A). This artifact was not massive, as in the first patient, but followed the course of the stent itself. Careful examination of the left pelvis with high-velocity scale showed a small artifact at the ureteropelvic junction. Unenhanced radiographic images confirmed the low position of the stent and showed only a thin calcified rim around both ends (Fig. 2B). The stent was withdrawn using a pulsed-dye laser. Chemical analysis of stone fragments showed calcium oxalate.



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Fig. 2A. 40-year-old pregnant woman (6 months) with thin encrustation of ureteral stent. Color Doppler sonogram of intravesical extremity of stent shows thin twinkling artifact only at posterior aspect of tube itself.

 


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Fig. 2B. 40-year-old pregnant woman (6 months) with thin encrustation of ureteral stent. Magnified unenhanced radiograph of lower end of stent shows thin calcified rim (arrows).

 


Discussion
Top
Introduction
Observations
Discussion
References
 
Stent replacement is particularly hazardous in pregnant patients because of the risk of inducing premature labor. The main reason for stent replacement is to avoid intrapelvic and intravesical encrustation of the stent extremities. The rate and speed of encrustation are variable, depending on the biochemical characteristics of urine and on the stent material [2, 3]. It occurs more frequently with polyurethane stents than with pure silicone ones. Hydrogel coating increases the rate of encrustation, particularly during pregnancy. Moreover, the salts and oxides of heavy metals (barium and bismuth) used as radioopacifiers may induce encrustation [7]. Therefore, the interval of time between stent replacements depends on stent type, among other factors.

Follow-up of stents by unenhanced radiography is recommended; even so, the encrustation phenomenon can be missed in its early phase. The second case reported here shows how difficult it can be to identify the thin calcified rim around the stent at the beginning of the phenomenon.

Encrustation usually occurs at the extremities of the stent. The lower extremity is easily identified within the bladder, because urine provides a useful contrast for identification of the twinkling artifact. The upper extremity may be more difficult to see within the pelvis if it is not dilated. In such a setting, differentiation between the hilar renal vessels and the twinkling artifact requires an increase in the Doppler pulse repetition frequency. This has no effect on the artifact [5] but decreases the Doppler signal. However, identification of encrustation at the lower end of the stent within the bladder should be sufficient, because it usually occurs symmetrically.

The artifact is frequently observed behind calcifications but is not constant. Rahmouni et al. [5] showed that it is generated by a random, strongly reflecting medium with a rough interface composed of individual reflectors. A relationship was shown in vitro between the surface of urinary stones and the presence of a twinkling artifact [6]. In most cases it appears when the surfaces of calculi are irregular (crystalline or mottled). In the case of encrustation, it is probable that a calcium phosphate or a calcium oxalate deposit makes the surface of the stent irregular or crystalline, thus creating the artifact. The second case shows how striking this artifact is within the bladder compared with the thin calcic rim visible with unenhanced radiography.

In summary, identification of encrustation of ureteral stents, one of the main complications of these materials, is possible with color-flow Doppler sonography in the presence of a twinkling artifact. The exact impact of sonographic follow-up on the urologic management of indwelling ureteral stents still remains to be defined.


References
Top
Introduction
Observations
Discussion
References
 

  1. Goldfarb RA, Neerhut GJ, Lederer E. Management of acute hydronephrosis of pregnancy by ureteral stenting: risk of stone formation. J Urol 1989;141:921 -922[Medline]
  2. Cox AJ, Hukins DWL. Morphology of mineral deposits on encrusted urinary catheters investigated by scanning electron microscopy. J Urol 1989;142:1347 -1350[Medline]
  3. Mardis HK, Kroeger RM, Morton JJ, Donovan JM. Comparative evaluation of materials used for internal ureteral stents. J Endourol 1993;7:105 -115[Medline]
  4. Kavoussi LR, Albala DM, Basler JVX, Apte S, Clayman R. Percutaneous management of urolithiasis during pregnancy. J Urol 1992;148:1069 -1071[Medline]
  5. Rahmouni A, Bargoin R, Herment A, Bargoin N, Vasile N. Color Doppler twinkling artifact in hyperechoic regions. Radiology 1996;199:269 -271[Abstract/Free Full Text]
  6. Chelfouh N, Grenier N, Higueret D, et al. Characterization of urinary calculi: in vitro study of "twinkling artifact" revealed by color-flow sonography. AJR 1998;171:1055 -1060[Abstract/Free Full Text]
  7. Pariente JL, Bordenave L, Bareille R, Baquey C, Le Guillou M. In vitro compatibility of radio-opacifiers used in ureteral endoprosthesis. Biomaterials 1999;20:523 -527[Medline]

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