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Fig. 1D. —69-year-old man with well-differentiated hepatocellular carcinoma (arrow, A and D) and severe cirrhosis. Gadolinium-enhanced hepatic arterial phase (A), equilibrium phase gradient-recalled echo (TR/TE, 150/1.6) (B), ferumoxide-enhanced respiratory-triggered T2-weighted fast spin-echo (5000/80) (C), and breath-hold T2^*-weighted gradient-recalled echo (150/10) (D) axial MR images fail to show tumor in B and C. Note that lesion conspicuity is better in A than in D, because of hepatic nodularity, ferumoxide uptake in tumor, and decreased ferumoxides uptake in liver due to cirrhosis.

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