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Fig. 1C. —53-year-old man with elevated prostate-specific antigen of 9.9 ng/mL and previous sextant biopsy with negative findings. Directed biopsy of right base and mid gland showed adenocarcinoma (Gleason score, 4 + 3). Transverse sonogram obtained during bolus administration shows focally increased parenchymal enhancement of right base (calipers). Targeted biopsy of this site yielded positive biopsy core.

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