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Fig. 1. —Graph shows composite receiver operating characteristic (ROC) curves for pooled data reviewed by three observers. Curves indicate relative accuracy with which hepatocellular carcinomas were detected on ferumoxides-enhanced () MR images of all five sequences (area under ROC curve [A_z] = 0.971 ± 0.013) and mangafodipir trisodium—enhanced () MR images of all four sequences (A_z = 0.950 ± 0.016). Difference in mean areas under curves was significant (p < 0.05).

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