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Fig. 9C. —Results of CT measurements and calculations with three-compartment model for contrast medium concentrations in vascular space and interstitium in 74-year-old patient with good renal function treated with right-sided percutaneous nephrostomy for ureteral stone. Volume of both kidneys was 578 mL. Glomerular filtration rate (GFR) measured by plasma clearance was 113 mL/min. CT GFR was 129 mL/min. Lower curve (A and B) represents contrast medium concentration in interstitial space. Parameters are more fully defined in Appendix 1. Graph shows amount of contrast medium as Patlak plot [3] resulting from three-compartment model () calculations. Interstitial space in patient was calculated as 11% of whole-kidney volume. Consequently, amount of contrast medium in interstitial space is much smaller than amount of contrast medium excreted into nephron, and calculated Patlak plot is almost a straight line. GFR calculated with Patlak plot is close to true GFR. = CT measurement.

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