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Fig. 7B. —52-year-old woman with extensive left breast carcinoma and overestimation of residual tumor by MRI after chemotherapy. Contrast-enhanced T1-weighted image obtained after chemotherapy shows decreased size and enhancement of mass, but persistent and extensive linear enhancement in breast, measuring 6.4 cm in anteroposterior dimension. Histologic evaluation of mastectomy specimen revealed 3.0-cm invasive and in situ ductal carcinoma. This size was smaller than predicted by MRI; however, pathologist commented that microscopic tumor deposits are present diffusely. It is very likely, therefore, that standard histologic size determination underestimated actual disease extent.

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