| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
|
|
|
|||||||
|
|||||||||
1 Division of Diagnostic Imaging, University of Texas M. D. Anderson Cancer
Center, 1515 Holcombe Blvd., Unit 56, Houston, TX 77030.
2 Present address: Department of Radiology, The Toledo Hospital, 2142 N Cove
Blvd., Toledo, OH 43606.
3 Department of Radiation Physics, University of Texas M. D. Anderson Cancer
Center, Houston, TX 77030.
4 Department of Radiology, University of Texas Medical School, 6431 Fannin St.,
MSB 2.100, Houston, TX 77030.
Received August 8, 2003;
accepted after revision October 8, 2003.
Address correspondence to D. D. Cody.
Abstract
 Top Abstract IntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
MATERIALS AND METHODS. Surface radiation dose measurements from a set of anthropomorphic phantoms (nominal 1 year old, 5 year old, and 10 year old) and an adult phantom were compared with standard CT dose index measurements. Image-noise values on axial 5-mm-thick anthropomorphic phantom images were obtained as a measure of image quality.
RESULTS. Peripheral CT dose index values obtained with the standard 16-cm acrylic phantom were within approximately 10% of the CT surface dose measurements for the pediatric anthropomorphic phantoms for both chest and abdominopelvic scan protocols. The noise value for the adult phantom image acquired using a typical clinical CT technique was identified, and targeting this level of noise for pediatric CT examinations resulted in a decrease in dose of 60–90%. Initially, 80 kVp was selected for use with very small children; however, beam-hardening artifacts were severe enough to cause us to abandon this option. Current pediatric protocols at M. D. Anderson Cancer Center rely on 100- and 120-kVp settings. The display field-of-view parameter can be used as a surrogate for patient size to develop clinical pediatric CT protocol charts.
CONCLUSION. CT dose index measurements obtained using the 16-cm standard acrylic phantom are sufficiently accurate for estimating chest and abdominopelvic CT entrance exposures for pediatric patients of the same approximate size as the anthropomorphic phantoms used in this study. Image-noise measurements can be used to adjust chest and abdominopelvic CT techniques for pediatric populations, resulting in a decrease in measured entrance dose by 60–90%.
|
TopAbstractIntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
Several schema are generally available for assigning an individual pediatric patient to a given set of CT scanning parameters, or protocol. Typically a combination of patient age, height, and weight are used for this purpose. At our institution, we have recognized that our pediatric patient population does not lend itself well to this approach. Our patients' body shapes are often affected by their disease or treatment or both, and they frequently present as either emaciated or bloated, neither of which would be appropriately compensated by an age, height, and weight approach to tailoring CT scanning protocols. Haaga et al. [5] and Haaga [6] have advocated the use of a patient's diameter to determine parameters such as X-ray tube current. The optimal variable to use for this protocol assignment would be the cross-sectional area presented to the scanning plane [7]. The display field of view used for the image reconstruction process is a reasonable surrogate for cross-sectional area. At our institution, the display field-of-view value is carefully tracked and is provided for follow-up examinations and is used to ensure consistent spatial scaling (magnification) from initial to follow-up scans. As the pediatric patient grows, the display field of view is increased as needed in increments of 4 cm to better fit the patient and maintain constant magnification for a significant period during growth.
For this pediatric CT optimization project, we placed surface dose monitors on adult and pediatric anthropomorphic phantoms, enabling us to compare entrance radiation doses among differently sized phantoms while we varied several technique parameters. Optimizing peak kilovoltage on the basis of patient size has been suggested as an alternative method to reducing radiation dose in CT because optimizing peak kilovoltage could potentially improve tissue contrast [8, 9]. Therefore, dose and noise measurements at 80-, 100-, 120-, and 140-kVp stations were examined. We selected the pediatric CT protocols that resulted in image-noise levels equivalent to those of typical adult CT scans, using combinations of scan parameters (peak kilovoltage and milliampere-second) that produced this equivalent image-noise level.
|
TopAbstractIntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
|
Five skin dose monitors were placed on the surface of each phantom. Three were positioned along the anterior midline of the phantom (above the mediastinal region), evenly spaced from the sternal notch to the level of the diaphragm and kidneys (exact placement varied with phantom size). Two skin dose monitors were placed along the lateral aspect of the torso of the anthropomorphic phantoms to yield more dose data with respect to the varying width of the subject (Table 1). All five dose detectors were well within the margins of the scanning field typical of a routine chest or abdominopelvic CT examination (Figs. 1B and 1C).
|
|
|
The skin dose monitors were calibrated using a standard CT ion chamber (PC4P, Capintec) and electrometer (Model 35080A Dosimetry System, Keithley Instruments) exposed in air at the isocenter of the CT scanner with several technique factors. The skin dose monitors were placed individually at the scanner isocenter and exposed in air using the same technique factors as those of the ion chamber. Exposure signals were carefully recovered for each device, and these calibration factors were used to convert the skin dose monitor output values to exposure on the ion chamber (ICa) scale, using the in-air readings. These calibration factors were the ratio of the ICa reading to the individual skin dose monitor reading at 80, 100, 120, and 140 kVp. Calibration in air was selected for converting the skin dose monitor data to the same scale as a standard CT ionization chamber dosimeter:
skin dose monitorIC = ICa (100-mm length / 20-mm overall beam width) / skin dose monitor in air,
where skin dose monitorIC refers to the skin dose monitor conversion factor to the ICa scale. ICa refers to the ion chamber measurement in air, and skin dose monitor in air refers to the "raw" value from the meter obtained in air. All skin dose monitor values shown in the Results section reflect the conversion process (essentially the surface dose monitor values were multiplied by the skin dose monitorIC factor).
The skin dose monitor measurements obtained at the surface of the anthropomorphic phantoms at 120 kVp were compared with the results using both 16-cm- and 32-cm-diameter CT dose index phantoms and a standard CT pencil ion chamber with the same acquisition parameters (peak kilovoltage, milliampere, and time). The skin dose monitor values were calibrated using the method described previously. Only peripherally located CT dose index data (ICp, in milliroentgens) were measured at 1 cm below the phantom surface to form a more equivalent comparison to the surface dose measurements obtained on the anthropomorphic phantoms. The result is a peripheral CT dose index value and is noted as CT dose indexp in this article. The f factor used in this study represents the conversion of exposure to dose for tissue (0.93 cGy/R) to more closely match the entrance dose measurements obtained using the tissue-equivalent anthropomorphic phantoms:
CT dose indexp = (ICp) (0.93 cGy / R) (100 mm) / (1,000 mR / R) (20-mm overall beam width).
Although the f factor does vary with X-ray beam energy, this effect for soft tissue is small (fewer than several percentage points) for our energy range (80–140 kVp). All CT dose index results reported in this study are CT dose index100 values.
All the anthropomorphic phantoms were scanned using anatomic landmarks for the inferior and superior scanning margins (start and stop locations) for chest and abdominopelvic examinations in the axial mode at 80, 100, and 120 kVp using 50, 100, 200, and 240 mAs at each peak kilovoltage setting. An additional set of measurements was obtained for the abdominopelvic scanning protocol with 140 kVp. This higher peak kilovoltage setting was added to the abdominopelvic protocols because we anticipated that the signal resulting from the abdominal attenuation pattern might benefit from the use of a higher peak kilovoltage X-ray beam. A measurement of image noise was also collected from a single image near the longitudinal midpoint of the scan series. The standard deviation within a circular region of interest (area, 554–565 mm2) placed in a specific location (a centrally located homogeneous region in the position of the heart for chest images and anterior to the spine for abdominopelvic images) in the resulting images was used as an indicator of image noise associated with the scanning protocol (Figs. 2A, and 2B). The amount of noise in the image can limit the visibility of low-contrast lesions. Image noise is also inversely proportional to the radiation dose to that region of the patient or phantom and is a parameter that can be used to compare image quality and dose among phantoms or people of different sizes.
|
|
Radiation dose can be decreased in CT in several ways, including a reduction in peak kilovoltage and milliampere-seconds. Because dropping peak kilovoltage can improve tissue contrast [8, 9], we were particularly interested in using this approach for children. Young patients typically have low visceral fat content relative to adults; this difference can make organ margin recognition somewhat challenging. We specifically examined decreasing the peak kilovoltage to as low as 80 kVp as one component of an optimized CT protocol for pediatric patients.
|
TopAbstractIntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
|
|
As expected, the dose to the pediatric anthropomorphic phantoms was considerably higher than the adult dose for the same CT scanning technique (Figs. 5 and 6). Surface dose has been normalized to the milliampere-seconds used for the scan for easier interpretation. The dose per unit milliampere-second for smaller patients was 1.6–1.7 times greater than that for an adult.
|
|
The noise measurements from the anthropomorphic phantoms depended on both the size of the phantom and the scanning parameters of peak kilovoltage and milliampere-seconds (Fig. 7). The noise in abdominopelvic images was notably greater than the noise in chest images, and this finding implies that chest CT examinations in pediatric patients should be designed with preferentially lower technique factors than abdominopelvic scanning protocols. The image noise was found to vary by a factor of as large as 3.3 among the different sizes of anthropomorphic phantoms when the same scanning acquisition parameters were used. The noise in the pediatric phantom images was generally one half to one third of the noise evident in the adult phantom images when the same scanning parameters were used for each group. The noise levels in the images of the adult phantom when scanned at a standard adult technique of 120 kVp and 200 mAs were considered acceptable and similar to levels in current CT images of patients (note that this reference adult noise value was approximately 7 H for this combination of scanning parameters).
|
The relationship between image noise and midline surface dose was nonlinear and provided the basis for the development of our current pediatric CT scanning protocols. The noise versus surface dose relationship for the anterior midline position (Figs. 8 and 9) was used to determine a target value for image noise: the noise in images of adults was matched to the equivalent image noise in images of children. For a standard adult scanning technique resulting in a noise value of approximately 7 H, the surface dose value corresponded to approximately 32 mGy at the sternum and approximately 43 mGy at the anterior surface of the abdomen. Considering this level of noise to be acceptable in the adult phantom images, we determined the anterior surface dose resulting in equivalent noise levels in each pediatric phantom by following the graph to the left and locating the point at which the pediatric curves intersected the 7-H noise value. For the 10-year-old phantom, a dose of approximately 9 mGy (chest CT) or 18 mGy (abdominopelvic CT) to the skin dose monitor resulted in the same noise level as that in the adult phantom images. Likewise, for the 5-year-old phantom, a dose of approximately 5 mGy (chest CT) or 15 mGy (abdominopelvic CT) to the skin dose monitor produced the same noise level as that in the adult phantom images. For the 1-year-old phantom, a dose of approximately 3.5 mGy (chest CT) or 7 mGy (abdominopelvic CT) to the skin dose monitor produced the same noise level as that in the adult phantom images. These graphs (Figs. 8 and 9) show that a noise equivalent CT image for pediatric patients can be obtained by reducing the dose by 60–90% relative to the scan technique used for adults.
|
|
A similar graph representing data obtained from the lateral surface position could be used for the same purpose (Figs. 10 and 11). Although the curves have the same general shape as in Figures 8 and 9, the elliptical shapes of the anthropomorphic phantoms can produce differences between midline and lateral surface dose results. The surface dose values obtained from the adult lateral positions are slightly lower than those obtained from the midline position for the same technique. A similar but much smaller difference was apparent among the pediatric anthropomorphic anterior midline versus lateral surface dose positions because of the more circular shape of the pediatric body cross-sections (Table 1). The lateral dose measurements were more consistent with the anterior midline results for the pediatric abdominopelvic CT examinations than was the case for chest CT examinations because the aspect ratio of the phantoms at the abdominopelvic location was more circular than that in the chest region.
|
|
On the basis of these results, we developed and implemented a pediatric
protocol table for thoracic CT imaging, in which a combination of decreasing
the peak kilovoltage and the milliampere-seconds was used to reduce the
radiation dose to pediatric patients. For each target surface dose value, we
could choose several combinations of peak kilovoltage and milliampere-seconds,
which would result in the same target dose measurement. Initially, the 80-kVp
setting (and its associated milliampere-seconds) was selected for the smallest
pediatric patients (those requiring a display field of view of 
23 cm),
the 100 kVp was selected for the middle-sized pediatric patients (display
field of view of 24–29 cm), and the standard 120 kVp was selected for
the larger pediatric patients (display field of view of 
29 cm). The use
of the 140-kVp option did not appear to have a clear advantage, so it was not
included in our initial protocol design.
Chest CT was performed using our initial protocol settings at 80 kVp on a 21-month-old patient for staging of cervical neuroblastoma (Fig. 12). Although the beam-hardening artifacts did not obscure anatomic detail in the lung region, prominent beam-hardening shadows were noted in the shoulder area that could obscure subtle soft-tissue lesions. Abdominal CT at 120 kVp was performed using our pediatric protocol before initiating this new program on a 4-year-old patient with stage V renal Wilms' tumor to monitor treatment effects (Fig. 13A) and again 2 months later at 80 kVp after launching our initial protocol settings (Fig. 13B). Beam-hardening artifacts were considered sufficiently severe to remove this option from our pediatric protocol chart. When the same patient was later scanned using a 100-kVp technique, the beam-hardening artifact was still present but substantially less noticeable (Fig. 13C). In addition to adjusting our protocol settings for peak kilovoltage, we have also made minor protocol changes to better compensate for changes in pitch. Our current pediatric protocol charts for both chest and abdominopelvic CT examinations are provided in Tables 2 and 3. Because it is important to use the maximal rotation speed available on a scanner platform for pediatric patients (to minimize patient motion artifacts), our protocol table is specific for each scanner platform, having a different minimal scanning time (0.8 or 0.5 sec). We expect to continue to adjust these settings as new technologies become available.
|
|
|
|
|
|
|
TopAbstractIntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
Our CT dose index approach yielded values that were within approximately 10% of the measured entrance exposure values for the pediatric phantoms for both chest and abdominopelvic CT examination protocols. This result should be considered within the context of the specific anthropomorphic phantoms used in this study (Table 1). The CT dose index phantoms are acrylic cylinders, whereas the anthropomorphic phantoms better represent patients but only at discrete sizes. This study effectively validated the CT dose index method for use in pediatric subjects when the 16-cm-diameter acrylic phantom was used. A rather unexpected finding was that the 16-cm-diameter acrylic CT dose index phantom also more accurately estimated the entrance dose measurements to the anterior midline of the adult anthropomorphic phantom than did the standard 32-cm acrylic CT dose index phantom (Figs. 3 and 4). The 32-cm CT dose index values, however, provided a better estimate of the lateral adult anthropomorphic phantom surface dose results than the 16-cm CT dose index phantom. Again, the size of the adult anthropomorphic phantom (Table 1) should be noted before making generalized conclusions regarding these results because it does not represent all possible adult sizes and shapes.
Like other researchers, we observed that smaller subjects receive higher doses than larger subjects when the CT technique factors are held constant [3, 8, 11]. The surface radiation exposure per unit milliampere-second can easily increase by almost 10-fold when scanning a nominal 1-year-old child with the technique applied for a nominal adult. This dose dependence on size is primarily due to higher exit dose contributions at the skin surface instead of the intensity of the X-ray beam entering at the surface. Larger subjects present more cross-sectional tissue to the X-ray beam, which causes more absorption and scattering of X-ray photons, diminishing the measured number and exit energy of the X-ray photons at the skin surface.
Any image-optimization process should include a careful evaluation of image quality; we have used the image-noise parameter as our primary end point in this respect [8]. Other parameters such as contrast-to-noise ratio might have been more useful, but the limited internal anatomic structural detail of these anthropomorphic phantoms (Figs. 2A, and 2B) would have made values such as contrast-to-noise ratio irrelevant to clinical applications.
Although the reduction of peak kilovoltage has been proposed as an attractive method for simultaneously reducing radiation exposure and improving tissue contrast [8, 9, 12, 13], this strategy was not completely successful in our clinical practice. Beam-hardening artifacts were sufficiently severe even in the smallest pediatric patients to warrant discontinuing the use of any pediatric protocols that included a peak kilovoltage setting less than 100 kVp.
The strengths of this study are that anthropomorphic phantoms produced from a single manufacturer representing a wide range of pediatric patients (1 year old, 5 year old, and 10 year old) were used and compared with results obtained on a nominal adult anthropomorphic phantom. Skin dose monitors (also applicable in clinical situations) were used to evaluate the radiation dose at the anterior surface midline and lateral locations of the torso of these anthropomorphic phantoms. The CT protocol technique parameters of peak kilovoltage and milliampere-seconds were used to explore surface dose and image quality tradeoffs for both chest and abdominopelvic examinations. Although this study was completed using only axial scanning acquisition modes, these results have been shown to be equivalent to helical acquisitions if pitch is held equal to 1 [11]. Dose estimates can reliably be scaled by pitch for extension to helical applications.
The weaknesses of this study include the fact that only a single image thickness (5 mm) was used. We selected the 5-mm-image-thickness setting for this study because we believed that this was perhaps the most commonly used slice thickness in routine clinical pediatric thoracic imaging. Measured dose values would be expected to vary with overall beam width. This detector configuration (4 x 5 mm) produced a 20-mm overall longitudinal X-ray beam width per rotation, which is the maximal coverage and most dose-efficient configuration for many MDCT scanners currently in the field, an important factor in pediatric CT imaging.
Although all noise measurements were collected from axial images, only helical acquisitions were selected for clinical implementation. The choice of helical mode is warranted in pediatric imaging because of examination time constraints, but helical images often contain more noise than axial images [14, 15]. The additional noise due to the interpolation component in helical image reconstruction should be assessed and incorporated before clinical implementation of this type of approach. Other parameters such as scan field of view (which may have affected the surface dose measurements) and display field of view (which may have affected noise measurements) were not addressed. This study could not be conducted with human pediatric subjects, and the images we obtained did not represent clinical imaging situations in many respects.
Future studies aimed at refining a CT scanning protocol for a given indication (e.g., the diagnostic task at hand for an individual patient) or range of indications may allow more precise use of CT in a pediatric population. CT scan techniques can and should be adjusted to better match the imaging task for individual patients [15]. Implementation of specific filters designed to reduce image noise associated with low-dose CT techniques may also prove clinically useful in pediatric populations [16, 17].
In this study, we analyzed image noise as a function of dose, CT technique, and phantom size. Our recommendations on CT technique for different patient sizes are based on maintenance of the noise at similar levels across all sizes. This image-noise criterion might not be clinically adequate because low-contrast structures in smaller patients are themselves smaller and might require increased signal-to-noise for adequate diagnosis. Our image-quality metric (image-noise) target reflects our specific patient population; as a cancer center, we consistently need to evaluate nearly all our patients for the presence of soft-tissue lesions. This challenging detection task is primarily the reason that our pediatric technique factors are somewhat higher than those that others have published [2, 3]. Also, because pediatric patients have lower fat content than adults, higher signal-to-noise ratio may be warranted to compensate for this difference. (The choice of a pitch less than unity for the larger patients in Table 2 reflects the need for a second set of thinner images and the limitations of the CT scanner. Only one choice of pitch and table speed was permitted on this scanner platform for this slice thickness to be available for the second image reconstruction process.) The purpose of this study was to investigate the relationship of noise, dose, size, and CT technique. Further clinical study is necessary to adequately transfer this knowledge to the clinical setting and may involve diagnostic and clinical factors beyond the scope of this project.
In summary, acceptable image quality can be achieved for pediatric patients by reducing the scanning technique parameters from those used for adults and thus reducing entrance radiation exposure by a relatively large amount. We found that the dose per unit milliampere-second on CT at constant scanning parameters can vary with the subject size by greater than a factor of 1.7 and that the associated image-noise value for a given technique can vary with subject size by a factor of up to 3.3. By matching the noise value currently considered acceptable in adult CT chest and abdominopelvic imaging, we decreased the pediatric skin dose by 60–90% relative to adults and produced acceptable image quality in our clinical pediatric CT images. A similar exercise is recommended for other institutions in which pediatric CT examinations are conducted. Parameters other than age, weight, and height, such as display field of view, can also be used successfully to stratify pediatric CT protocol parameter ranges.
|
TopAbstractIntroductionMaterials and MethodsResultsDiscussionReferences |
|---|
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
This article has been cited by other articles:
|
|
 |
|
  S V VOLLMAR and W A KALENDER Reduction of dose to the female breast as a result of spectral optimisation for high-contrast thoracic CT imaging: a phantom study Br. J. Radiol., November 1, 2009; 82(983): 920 - 929. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Herzog, D. M. Mulvihill, S. A. Nguyen, G. Savino, B. Schmidt, P. Costello, T. J. Vogl, and U. J. Schoepf Pediatric Cardiovascular CT Angiography: Radiation Dose Reduction Using Automatic Anatomic Tube Current Modulation Am. J. Roentgenol., May 1, 2008; 190(5): 1232 - 1240. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Tubiana, S. Nagataki, L. E. Feinendegen, D. A. Dimitroyannis, D. P. Frush, M. J. Goske, M. Hernanz-Schulman, P. Soyer, H. Varnholt, D. J. Brenner, et al. Computed Tomography and Radiation Exposure N. Engl. J. Med., February 21, 2008; 358(8): 850 - 853. [Full Text] [PDF]
|
|
|
|
|
|
J. D. MacKenzie, J. Nazario-Larrieu, T. Cai, M. S. Ledbetter, M. A. Duran-Mendicuti, P. F. Judy, and F. J. Rybicki Reduced-Dose CT: Effect on Reader Evaluation in Detection of Pulmonary Embolism Am. J. Roentgenol., December 1, 2007; 189(6): 1371 - 1379. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W Mazrani, K McHugh, and P J Marsden The radiation burden of radiological investigations Arch. Dis. Child., December 1, 2007; 92(12): 1127 - 1131. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. M. Heyer, P. S. Mohr, S. P. Lemburg, S. A. Peters, and V. Nicolas Image Quality and Radiation Exposure at Pulmonary CT Angiography with 100- or 120-kVp Protocol: Prospective Randomized Study Radiology, November 1, 2007; 245(2): 577 - 583. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. R. Long High-Resolution Computed Tomography of the Lung in Children with Cystic Fibrosis: Technical Factors Proceedings of the ATS, August 1, 2007; 4(4): 306 - 309. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K Fujii, T Aoyama, S Koyama, and C Kawaura Comparative evaluation of organ and effective doses for paediatric patients with those for adults in chest and abdominal CT examinations Br. J. Radiol., August 1, 2007; 80(956): 657 - 667. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Z A Aziz, J C Davies, E W Alton, A U Wells, D M Geddes, and D M Hansell Computed tomography and cystic fibrosis: promises and problems Thorax, February 1, 2007; 62(2): 181 - 186. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. H. McCollough, M. R. Bruesewitz, and J. M. Kofler Jr CT Dose Reduction and Dose Management Tools: Overview of Available Options. RadioGraphics, March 1, 2006; 26(2): 503 - 512. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. H. Mulkens, P. Bellinck, M. Baeyaert, D. Ghysen, X. Van Dijck, E. Mussen, C. Venstermans, and J.-L. Termote Use of an Automatic Exposure Control Mechanism for Dose Optimization in Multi-Detector Row CT Examinations: Clinical Evaluation Radiology, October 1, 2005; 237(1): 213 - 223. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. O'Daniel, D. M. Stevens, and D. D. Cody Reducing Radiation Exposure from Survey CT Scans Am. J. Roentgenol., August 1, 2005; 185(2): 509 - 515. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Boone What Parameters Are Most Accurate in Predicting Appropriate Technique Factors for CT Scanning? Radiology, August 1, 2005; 236(2): 377 - 378. [Full Text] [PDF]
|
|
|
|
|
|
M. J. Siegel, B. Schmidt, D. Bradley, C. Suess, and C. Hildebolt Radiation Dose and Image Quality in Pediatric CT: Effect of Technical Factors and Phantom Size and Shape Radiology, November 1, 2004; 233(2): 515 - 522. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J.-F. Paul, H. T. Abada, A. Sigal-Cinqualbre, E. Lee, and M. Siegel Should Low-Kilovoltage Chest CT Protocols Be the Rule for Pediatric Patients? Am. J. Roentgenol., October 1, 2004; 183(4): 1172 - 1172. [Full Text] [PDF]
|
|
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| HOME | HELP | FEEDBACK | SUBSCRIPTIONS | ARCHIVE | SEARCH | TABLE OF CONTENTS |
=
adult phantom, 
= 10-year-old phantom, 
= 5-year-old phantom,
= 1-year-old phantom, # = 16-cm CT dose index phantom, 
= 32-cm
CT dose index phantom.
