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Fig. 3B. Diagrams of lung neoplasm before and after radiofrequency ablation. Diagram shows same tumoral lung lesion after radiofrequency ablation. Area of enzymatic necrosis with partially destroyed capillaries, microthrombosis, and lysosomal enzyme activation is labeled D. Peripheral ring of this area (D1) appears to express presence of microhemorrhagic border mixed with outermost layer (E), with edema, inflammatory reaction, and vascular congestion. A = central area intersected by electrode needle; B = partial emptying (dark), likely due to vaporization of lesion, and coagulative necrotic area with destroyed capillaries and "ghost phenomenon" (term used by Miao et al. [29] to describe seemingly intact tissue after sudden thermal coagulation); C = coagulative necrotic area surrounding nodule and containing collapsed alveoli with entrapped air and ghost phenomenon.





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