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Fig. 2C. —67-year-old woman with unifocal tumor that fragmented while
she underwent chemotherapy. MR images obtained after two courses (B)
and at end of chemotherapy (C) show fragmentation of tumor, resulting
in multiple residual foci. MRI measurement of longest tumor diameter
underestimated residual 6-cm invasive ductal carcinoma tumor by 2 cm. This
type of response was considered to indicate unfavorable situation for
breast-conserving surgery. In this patient, MRI assessment would have led to
postchemotherapy mastectomy and allowed her to avoid undergoing additional
breast-conserving surgery that resulted in positive margins.
