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Fig. 1E. 38-year-old man with classic adamantinoma of tibia.
Radiologic diagnosis of fibrous dysplasia was established at 2 years old in
1961. At 6 years old, he had fracture, and anterior bowing developed after
cast removal. Three years after en bloc resection in 1996, he developed
recurrent tumor and lung metastases and died. Photomicrographs of lesion after
resection show bulging and thinning of cortical bone (C, D) by tumor
(T, D) and cortical breakthrough and invasion of surrounding thickened
periosteum (P, E). (H and E, x50)