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Fig. 1B. —Drawings show recording of spreading depression in mouse
cerebral hemispheres. Pair of traces represent 30-min interval of recurrent
spreading depression, while simultaneously measuring relative blood flow
(higher trace) and DC potential deflections (lower trace) using dural surface
electrode. Blood flow changes were measured with transcranial laser Doppler
probe and DC potentials with silver chloride ball electrode applied directly
to brain surface. Mean ± SD of 16 ± 3 spreading depressions were
recorded (n = 10) in right cerebral hemisphere over 2-hr period.
