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Fig. 3D. 24-year-old man with primary lymphoma of bone of distal
metaepiphysis of femur and histologically proven, probably radiation-induced,
necrosis adjacent to primary tumor site (patient 2). Coronal proton
density-weighted fat-saturated image (3,950/45) obtained 16 months after start
of radiation therapy shows new signal abnormalities in field of therapy
adjacent to primary tumor site (straight arrows). Susceptibility
artifacts (curved arrow) are due to surgical biopsy. Pathologic
examination after biopsy revealed necrosis and scar tissue without any tumor
cells.