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Fig. 1A. ETherm computer simulation model template [5]. These computer simulations were used to generate heating profiles for 12 min of radiofrequency application using 3-cm tip, 17-gauge internally cooled electrode and 2,000-mA output generator. Radiofrequency electrode (blue line) is centered within variable-sized cylinder (colored rectangles, arrow) representing tumors of variable radius. Inner compartment radius and electrical conductivity were varied (r = 5-30 mm and {sigma}[I] = 0.07-14 S/m = siemens per meter, respectively) compared with background electrical conductivity ({sigma}[O] = 0.12 S/m = siemens per meter) of liver [9].





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