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Fig. 4C. Illustration of final Cox model using Kaplan-Meier curves for length of recurrence-free survival (RFS). Resulting model from stepwise Cox analysis showed initial MRI tumor volume (p = 0.0051) and final change in MRI tumor volume (p = 0.0028) to be most significant independent predictors. {downarrow}Vol = volume decrease. Significantly longer RFS was observed in group of patients with initial tumor volumes less than 33 cm3 and at least 50% reduction in tumor volume during treatment (96% 2-year RFS, n = 23) compared with other patients (60% 2-year RFS, n = 35; p = 0.032, Wilcoxon's test).





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