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Fig. 2B. —50-year-old woman with invasive ductal carcinoma, grade III,
studied while undergoing neoadjuvant chemotherapy treatment. MRI was performed
using contrast-enhanced 3D fast gradient-recalled echo pulse sequence (TR/TE,
8/4.2; flip angle, 20°; 18-cm field of view, 2-mm slice thickness, 256
x 192 acquisition matrix). Patient presented with 22 cm3
(4.7-cm diameter) tumor. Significant reduction in MRI tumor volume was evident
after one cycle of chemotherapy (30% decrease) and by end of treatment (88%
decrease). Patient had 2.2 cm of residual disease and one involved lymph node
at surgery and continues to be disease-free 20 months after surgery. Maximum
intensity projection (top) with corresponding tumor volume
segmentation for representative sagittal slice (bottom) acquired
after one cycle of chemotherapy.
