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Fig. 6B —Schematic representations of ablated lesion immediately after
radiofrequency ablation. Histopathologically, ablated lesion presents
three-layered structure, outermost layer (hemorrhagic rim) mainly consists of
congestion (C); intermediate layer mainly consists of effusion in pulmonary
alveoli lumens (E); and innermost portion mainly consists of cytoplasm, which
shows acidophilic change and nuclei that have condensed chromatin (N). Maximum
diameter on macroscopic (macro) examination is measured. Completely necrotic
lesion is intermediate layer and innermost portion (E + N). Maximum diameter
on macroscopic examination is inner necrotic lesion plus outermost layer
(hemorrhagic rim). Maximum diameter on CT and on macroscopic examination is
significantly correlated. Therefore, area with ground-glass attenuation on CT
leads to overestimation of necrotic lesion.
