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Fig. 1B MR images of typical patient with Merkel cell carcinoma show one unique imaging finding of Merkel cell carcinoma: positive anatomic alignment of subcutaneous lymphatic tumor nodules. Patient is 63-year-old man with primary tumor in skin of right popliteal fossa. Corresponding axial STIR image (4,800/60; inversion time, 180 msec) shows high signal intensity of skin and subcutaneous lymphatic metastases (small arrows), an example of positive anatomic alignment of subcutaneous lymphatic tumor nodules. Marked reticular stranding in subcutaneous fat is also seen. Histologically these two findings were shown to represent lymphangitis carcinomatosa. Lymph node metastases (large arrow) are seen adjacent to proximal superficial femoral artery.





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