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Fig. 1 —Definition of computer-assisted diagnosis (CAD)-generated
variables. Curve 1 (bold line) represents a pixel that did not
increase to level of significant enhancement on immediate contrast-enhanced
series. This pixel would not be enhanced on CAD overlay, regardless of pixel
value on delayed contrast-enhanced series. Curve 2 (dotted line)
represents a pixel that did increase to level of significant enhancement and
continued to increase on delayed series to a value more than 10% higher than
its value on immediate contrast-enhanced series. This pixel would be colored
blue to represent significant and persistent enhancement. Curve 3 (dashed
line) represents a pixel that increased to level of significant
enhancement and then decreased by more than 10% on delayed contrast-enhanced
series. This pixel would be colored red to represent significant and washout
enhancement.
