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Fig. 4C —13-year-old girl with distal femoral osteosarcoma. Image shown in
B with regions of interest (circled areas) outlining inner and
outer halves of tumor. Tumor periphery was outlined by radiologist. Computer
software then divided tumor area into inner and outer halves, and dynamic
vector magnitude (measure of both initial rate of contrast uptake and maximum
contrast enhancement) and kep (measure of exchange rate of contrast
agent between plasma and extracellular fluid space) for these regions were
determined.
