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Fig. 2B 52-year-old woman with family history of breast cancer who underwent
high-risk-screening MRI. Sagittal image from T1-weighted 3D fat-suppressed
fast spoiled gradient-echo sequence (17/2.4; flip angle, 35°) after IV
contrast administration on day of biopsy shows clumped ductal enhancement
(arrow) at 6-o'clock axis. Round signal void within clumped
enhancement is from biopsy obturator, which is in center of enhancement.
Histologic examination of MRI vacuum-assisted breast biopsy specimens showed
atypical ductal hyperplasia with adenosis and stromal fibrosis. Histologic
examination of surgical specimen revealed ductal carcinoma in situ, solid and
cribriform types, intermediate nuclear grade, in background of atypical ductal
hyperplasia.