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Fig. 1J —19-year-old man (A-E) and 56-year-old man
(F-J) with glioblastoma multiforme. Serial increases in MR
signal intensity after successful convection-enhanced infusion in two patients
with little or no preexisting signal abnormality directly at catheter tip. In
both patients morphology of region of hyperintense signal abnormality on MRI
closely matches distribution of infusate seen on SPECT. Human figure indicates
imaging plane. Blue line indicates plane perpendicular to tip of catheter.
Green line indicates catheter trajectory. Superimposition on I of
intraparenchymal distribution from 48-hour 123I-human serum albumin
SPECT at 50% isodose level (green).
