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Fig. 3B —61-year-old man with hepatocellular carcinoma and lack of
correlation between 
-fetoprotein levels and imaging response to
90Y microspheres. Axial arterial phase contrast-enhanced CT image
obtained 1 month after 90Y treatment shows complete necrosis and
increased size (7.5 x 4.6 cm) of lesion (arrow).
Alphafetoprotein level increased to 568 ng/mL and then decreased to 271 ng/mL
1 month later. This example shows that increase in lesion size associated with
necrosis is not indicative of disease progression. In addition, it shows that
transient increase in -fetoprotein level may be due to tumor lysis and
not worsening disease.
