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Fig. 5 52-year-old man with strong family history of premature death
due to aneurysm; genetic testing confirmed Loeys-Dietz syndrome. Axial IV
contrast-enhanced MDCT scan shows aneurysmal dilatation of left anterior
descending coronary artery (arrows). Other findings (not shown)
included rapidly increasing aortic root aneurysm, infrarenal abdominal aortic
and iliac artery aneurysms, and tortuous vertebral and extracranial carotid
arteries. Aortic root and aortoiliac aneurysms were surgically repaired,
revealing cystic medial degeneration of thoracic aorta and marked elastic
fiber fragmentation of abdominal aorta at pathology.