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Figure 9


Fig. 5 52-year-old man with strong family history of premature death due to aneurysm; genetic testing confirmed Loeys-Dietz syndrome. Axial IV contrast-enhanced MDCT scan shows aneurysmal dilatation of left anterior descending coronary artery (arrows). Other findings (not shown) included rapidly increasing aortic root aneurysm, infrarenal abdominal aortic and iliac artery aneurysms, and tortuous vertebral and extracranial carotid arteries. Aortic root and aortoiliac aneurysms were surgically repaired, revealing cystic medial degeneration of thoracic aorta and marked elastic fiber fragmentation of abdominal aorta at pathology.





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