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Fig. 2B —58-year-old man with 9-mm solid nodule with irregular margins
on surveillance CT scan obtained 15 months after baseline CT (cancer # 2). For
CT examinations, t, t–1, and t–2, respectively, designate current,
most recent prior examination, and second most recent prior examination.
Numbers marked with C are automatically generated by computer-aided detection
(CAD) system and indicate presence of nodule candidate. On image from first
follow-up CT at time t–1 (457 days), there is now an 8.6-mm irregular
spiculated nodule at same location. CAD detected and marked this lesion on
this and subsequent examination (C) (green circles, B
and C).