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Figure 15


Fig. 9 Monitoring early rheumatoid arthritis activity. Schematic of quantitative evaluation of rate of synovial enhancement before (solid line) and after (dotted line) effective treatment. Data were derived from contrast-enhanced dynamic MRI scans. Synovial enhancement is defined as SItSI0 / {Delta}t, where SIt is signal intensity obtained t seconds after contrast injection, SI0 is signal intensity obtained in first unenhanced image, and {Delta}t is time taken to reach peak enhancement over initial linear phase (dotted area). After treatment, synovitis and therefore synovial enhancement are reduced.





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