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Myxoid Sarcoma Versus Aggressive Angiomyxoma

Hospital of the University of Pennsylvania, Philadelphia, PA

 
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The report by Benjaminov and colleagues [1] of an unusual presentation of a myxoid liposarcoma describes characteristic signs, symptoms, and imaging features of a different myxoid neoplasm. Aggressive angiomyxoma classically presents as a perineal mass in young women. At imaging or surgery, the mass is shown to have pelvic components [2]. In a previous AJR article, Outwater et al. [2] (Fig. 1) showed a woman with MRI findings similar to the current case [1] (Fig. 2). Pathologists can have difficulty in distinguishing among the various myxoid soft-tissue tumors [3]. In this instance, radiologists can become virtual pathologists and determine the correct tissue signature [4]. Could the pathology be reviewed again? If the diagnosis of aggressive angiomyxoma is confirmed, then the now 27-year-old woman should be informed of her revised diagnosis and that she did not have a sarcoma removed 3 years ago.

View larger version (167K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 1 —23-year-old woman with aggressive angiomyxoma extending from perineum to upper pelvis. Sagittal T2-weighted fast spin-echo MR image shows large tumor (arrows) with high signal intensity interspersed with swirled strands of lower signal intensity. (Reprinted from [2])

View larger version (126K): [in this window] [in a new window] [as a PowerPoint slide]   Fig. 2 —24-year-old obese woman with mass in left buttock. Sagittal T1-weighted image obtained with fat saturation shows high-signal-intensity mass (asterisks) with no evidence of tissue fat within it. C = cystic areas within the mass. (Reprinted from [1])

References

Top References

 

1. Benjaminov O, Gutman H, Nyabanda R, Keinan R, Sabach G, Levavi H. Myxoid liposarcoma: an unusual presentation. AJR2007; 188:817 -821[Free Full Text]
2. Outwater EK, Marchetto BE, Wagner BJ, Siegelman ES. Aggressive angiomyxoma: findings on CT and MR imaging. AJR1999; 172:435 -438[Abstract/Free Full Text]
3. Ninfo VV, Montesco MC. Myxoid tumors of soft tissues: a challenging pathological diagnosis. Adv Clin Path1998; 2:101 -115[Medline]
4. Rogers LF. Imaging: a sisyphean search for the elusive tissue signature. AJR 2002;179 : 557[Free Full Text]

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This Article Figures Only Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Siegelman, E. S. Search for Related Content PubMed PubMed Citation Articles by Siegelman, E. S. Social Bookmarking                      What's this?