Cine Loops

Fig. S2C—91-year-old man with hepatocellular carcinoma. Cine loop conventional contrast-enhanced sonographic image shows only heterogeneous bright ball of enhancement with no vessel detail as contrast agent rapidly fills entire vascular bed.

Fig. S2D—91-year-old man with hepatocellular carcinoma. Cine loop maximum-intensity-projection image obtained 0.5 second after flash shows morphologic features of individual tumor vessels.

Fig. S3C—24-year-old asymptomatic woman with focal nodular hyperplasia. Cine loop maximum-intensity-projection image obtained 0.4 second after flash shows stellate vessels and centrifugal filling pattern.

Fig. S4C—45-year-old man with poorly differentiated adenocarcinoma. Cine loop conventional sonographic image obtained during wash-in of contrast agent shows isolated bubbles within tumor without vessel detail.

Fig. S4D—45-year-old man with poorly differentiated adenocarcinoma. Cine loop maximum-intensity-projection image obtained 5.8 seconds after flash shows vessel detail within hypoperfused lesion.

Fig. S5—35-year-old man with hemangioma. Cine loop shows maximum-intensity-projection image obtained 9.4 seconds after onset of arterial phase enhancement shows puddles of contrast material around periphery of lesion.

Fig. S6—54-year-old man with incidental small hemangioma. Cine loop maximum-intensity-projection image of normal liver vasculature shows accumulated enhancement over 11 seconds after contrast material arrives in liver. Unprecedented depiction of vessel structure to fifth order branching is evident. Focal unenhanced region is slowly perfusing hemangioma, which does not have contrast accumulation, making diagnosis impossible.

Files in this Data Supplement:

• Fig. S2C - Fig. S2C
• Fig. S2D - Fig. S2D
• Fig. S3C - Fig. S3C
• Fig. S4C - Fig. S4C
• Fig. S4D - Fig. S4D
• Fig. 5 - Fig. S5
• Fig. 6 - Fig. S6