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Fig. 1B —Histopathologic photomicrographs of 65-year-old man (patient
2 in Table 1) who developed
clinical symptoms of nephrogenic systemic fibrosis 2 months after IV
administration of MR contrast material. Patient had urinary tract infection at
time of contrast administration. (Courtesy of John Patrick, Greensboro, NC) H
and E stain (x60 magnification) shows increased number of delicate
S-shaped and plump spindled fibroblasts and very little associated
inflammation. These findings are consistent with nephrogenic systemic
fibrosis.
