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Fig. 1 —Graph shows initial and follow-up volumes in hippocampus with
abnormal signal intensity on initial imaging (patients 1–7 in
Table 1). For patient 2, solely
hippocampus with most abnormal signal intensity is depicted. Children with
solely normal hippocampal signal intensity (patients 8–11) are not
included in this graph. Each child's hippocampus is denoted by single color
different from other children; numbers in graph correlate to patient numbers
in Table 1. Graph compares
hippocampal volume change over time with growth curve of normal hippocampal
volumes (black line) generated from normal MR scans of 30 children of
various ages who had no history of developmental delay or seizures. Varying
degrees of hippocampal volume decrease are seen in six of seven children.
Furthermore, degree of volume loss is most marked in patients 1–3, who
had moderate or severe signal abnormality within hippocampus represented
here.
