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DOI:10.2214/AJR.07.3898
AJR 2008; 191:W75
© American Roentgen Ray Society

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Yue-Yong Xiao, Jin-Lin Tian and Jin-Shan Zhang

Chinese PLA General Hospital Beijing, China
Chinese PLA 252 Hospital BaoDing Hebei Province, China
Chinese PLA General Hospital Beijing, China



 
WEB—This is a Web exclusive article.

We are pleased with the response to our article [1] and appreciate the two important points regarding contrast media and the double-oblique puncture approach raised by Dr. De Filippo and colleagues [2]. As for the first point, we wrote in the Procedure portion of the Material and Methods section of our article, "For small lesions (< 3 cm), alcohol was used for the ablation. For large tumors (> 3 cm), a 50% acetic acid solution (99.9% acetic acid added the half of iodized oil) was used." The contrast medium used to mix with acetic acid was iodized oil, and the quantity of iodized oil was the half of the acetic acid calculated on the basis of the formula, {nu} = 4/{pi} (R + 0.3)3.

As for guidance, CT is a good imaging technique for adrenal chemical ablation because of its higher resolution and accurate localization [3, 4]. In our study, CT was performed with LightSpeed 16 helical scanners (GE Healthcare). Actually, the double-oblique approach was widely used in our many CT-guided procedures. The double-oblique approach includes medial–lateral and cranial–caudal (or caudal–cranial) oblique angles; the former can be measured by axial images, and the latter is the gantry oblique angle.

In the left adrenal gland, when the lesion is small (< 2 cm) and occasionally the abdominal aorta and left kidney are very near the gland, the double-oblique approach could be used to avoid penetrating adjacent organs, although there is a possibility of inserting the needle through the lung and diaphragm. When a fine needle (22-gauge) was used, usually no complications occurred even if the needle was inserted through the lung and diaphragm. We even punctured the left adrenal gland through the lung and diaphragm in several cases. No pneumothorax or respiratory movement disorders occurred (Fig. 1).


Figure 1
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Fig. 1 MDCT-guided chemical ablation in 42-year-old man with functional pheochromocytoma in left adrenal gland. On native axial view, needle was inserted through lung and diaphragm into adrenal gland (arrowhead). No pneumothorax or respiratory movement disorders occurred after puncture. L = lung, D = diaphragm.

 
In our study [1], the positions of left adrenal lesions were high, and it was not necessary to scan with a cranial–caudal angle. Thus the design of the needle path should depend on the position of the lesions and their anatomic relationship to the adjacent organs.


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References
 

  1. Xiao YY, Tian JL, Li JK, et al. CT-guided percutaneous chemical ablation of adrenal neoplasms. AJR 2008;190 : 105-110[Abstract/Free Full Text]
  2. De Filippo M, Onniboni M, Zompatori M. Double-oblique approach for MDCT-guided needle biopsy or ablation in adrenal tumors using multiplanar reconstruction. (letter) AJR 2008;191 :[web] W74[Free Full Text]
  3. Mayo-Smith WW, Dupuy DE. Adrenal neoplasms: CT-guided radiofrequency ablation—preliminary results. Radiology 1999;213 : 612-615[Abstract/Free Full Text]
  4. Liang HL, Pan HB, Lee YH, et al. Small functional adrenal cortical adenoma: treatment with CT-guided percutaneous acetic acid injection—report of three cases. Radiology2004; 231:225 -230[Abstract/Free Full Text]

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