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Fig. 4 —On chart, different behaviors of correlation of apparent
elastic modulus with square of bone volume-to-total volume ratio fraction
parameter can be observed depending on analyzed volume of interest (VOI).
Small VOI samples present no relationship of dependence with square of bone
volume-to-total volume ratio fraction parameter. Large VOI samples have linear
behavior and high correlation between apparent elastic modulus and square of
bone volume-to-total volume ratio. 
= large VOI, 
= small VOI.
