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DOI:10.2214/AJR.08.2243
AJR 2009; 193:W77
© American Roentgen Ray Society

Prone Breast Dual-Time-Point PET/CT Compared With MRI for Determining Breast Cancer

Gerald Q. Maguire, Jr.

Royal Institute of Technology, Stockholm, Sweden

Marilyn E. Noz and Fabio Ponzo

New York University School of Medicine, New York, NY



 
WEB—This is a Web exclusive article.

We compliment Imbriaco et al. [1] on their well-presented article on the use of dual-time-point PET/CT standardized uptake values to distinguish malignant from benign breast lesions. The authors used a prone technique to compare lesions seen on MRI with lesions seen at both time points on the prone PET/CT breast scans. However, in the Discussion section the authors state, "Finally, to our knowledge, this is the first study in the English-language literature to directly compare 18F-FDG PET/CT performed in the prone position and breast MRI in patients with suspected breast cancer."

We would like to point out that this indicates that the authors overlooked the work of many other researchers. In 1999, in the AJR Yutani et al. [2] report results on prone breast PET. Admittedly, they did not compare their results to MRI. However, Imbriaco et al. [1] do cite as their reference 35 the article by Goerres et al. [3] in which prone PET/CT images were most certainly compared with breast MRI. Furthermore, there are two recent articles by Moy et al. [4, 5] in which not only is prone breast PET/CT compared with MRI, but also the 3D volume data sets were registered and super-imposed for a better comparison of the breast lesions. This is not meant to be an exhaustive list but merely an indication that prone PET/CT and MRI have been compared previously in the English-language literature.


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  1. Imbriaco M, Caprio MG, Limite G, et al. Dual-time-point 18F-FDG PET/CT versus dynamic breast MRI of suspicious breast lesions. AJR 2008;191 : 1323-1330[Abstract/Free Full Text]
  2. Yutani K, Tatsumi M, Uehara T, Nishimura T. Effect of patients' being prone during FDG PET for the diagnosis of breast cancer. AJR 1999; 173:1337 -1339[Free Full Text]
  3. Goerres GW, Michel SC, Fehr MK, et al. Follow-up of women with breast cancer: comparison between MRI and FDG PET. Eur Radiol 2003; 13:1635 -1644[CrossRef][Medline]
  4. Moy L, Ponzo F, Noz ME, et al. Improving specificity of breast MRI using prone PET and fused MRI and PET 3D volume datasets. J Nucl Med 2007; 48:528 -537[Abstract/Free Full Text]
  5. Moy L, Noz ME, Maguire GQ Jr, et al. Prone mammoPET acquisition improves the ability to fuse MRI and PET breast scans. Clin Nucl Med 2007; 32:194 -198[CrossRef][Medline]

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Am. J. Roentgenol., July 1, 2009; 193(1): W78 - W78.
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