DOI:10.2214/AJR.08.2393
AJR 2009; 193:W78
© American Roentgen Ray Society
Reply
Massimo Imbriaco,
Francesca Soscia and
Giuseppe Avitabile
University Federico II, Napoli, Italy
WEB—This is a Web exclusive article.
We thank Maguire et al. [1]
for their interest and comments regarding our article "Dual-Time-Point
18F-FDG-PET/CT Versus Dynamic Breast MRI in the Preoperative
Evaluation of Suspicious Breast Lesions"
[2]. We will try to comment on
each of their concerns.
The peculiarity of our manuscript is that we used a dual-time-point PET/CT
technique in a selected group of patients with newly diagnosed breast cancer,
and we did not look at patients with recurrence of disease.
In the study by Moy et al.
[3], the authors compared MRI
alone with fused MRI and PET in a lesion-by-lesion analysis to increase the
specificity of breast MRI for detecting invasive breast cancer. The authors do
not report results comparing breast MRI alone with PET alone. It is true that
in the second article by Moy et al.
[4], published in Clinical
Nuclear Medicine, the authors compared prone acquisition PET using
traditional supine acquisition with MRI to improve evaluation of enhancing
lesions detected on MRI. However, in both of these articles, there is no
direct comparison of the dual-time-point 18F-FDG PET/CT technique
(as performed in our study) with breast MRI. Finally, in the article by
Goerres et al. [5], the authors
compared MRI of the breast with FDG PET in the follow-up of women with
suspected recurrence of breast cancer. Conversely, in our article, we directly
compared dual-time-point FDG PET with MRI in patients with suspected breast
cancer. In addition, the authors use FDG PET alone and not a PET/CT technique
as was used in our study, and, again, there was no direct comparison of
dual-time-point FDG PET/CT with breast MRI.
References
- Maguire GQ Jr, Noz ME, Ponzo F. Prone breast dual-time-point PET/CT
compared with MRI for determining breast cancer. (letter)
AJR 2009;193
:[web] W77[Free Full Text]
- Imbriaco M, Caprio MG, Limite G, et al. Dual-time-point
18F-FDG PET/CT versus dynamic breast MRI of suspicious breast
lesions. AJR 2008;191
: 1323-1330[Abstract/Free Full Text]
- Moy L, Ponzo F, Noz ME, et al. Improving specificity of breast MRI
using prone PET and fused MRI and PET 3D volume datasets. J Nucl
Med 2007; 48:528
-537[Abstract/Free Full Text]
- Moy L, Noz ME, Maguire GQ Jr, et al. Prone mammoPET acquisition
improves the ability to fuse MRI and PET breast scans. Clin Nucl
Med 2007; 32:194
-198[CrossRef][Medline]
- Goerres GW, Michel SC, Fehr MK, et al. Follow up of women with
breast cancer: comparison between MRI and FDG PET. Eur
Radiol 2003; 13:1635
-1644[CrossRef][Medline]
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