OBJECTIVE. The use of thrombolytic agents and other forms of
reperfusion therapy has provided a means to reverse ischemia and minimize the
size of infarctions. The purpose of this review is to examine various clinical
trials of reperfusion agents and address key imaging issues.
CONCLUSION. Advanced MRI and CT play a growing role in selection of
patients for therapy. Numerous clinical trials have shed light on the efficacy
of various reperfusion therapies; disparities in trial design have also left
unanswered questions.
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