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Research Article
Article
November 23, 2012

TOXICITY STUDIES ON TANNIC ACID ADMINISTERED BY ENEMA : III. STUDIES ON THE RETENTION OF ENEMAS IN HUMANS IV. REVIEW AND CONCLUSIONS

Abstract

1. The present investigation shows that subjects given a cleansing enema solution containing tannic acid in a concentration of 0.25 per cent will, on the average, retain no more than 25 per cent of the instilled volume for longer than 20 minutes.
2. Subjects given a barium enema solution containing tannic acid in a concentration of 0.25 per cent will, on the average, retain no more than 25 per cent of the instilled volume for longer than 35 minutes.
3. Certain patients in both groups, however, may retain at least 25 to 40 per cent of
[See table in the PDF file]
the administered cleansing or barium enema after colonic evacuation is judged complete by the subject. This retention may persist beyond 30 minutes in those persons receiving cleansing enemas and 45 minutes in those receiving barium enemas.

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Information & Authors

Information

Published In

American Journal of Roentgenology
Pages: 505 - 509

History

First published: November 23, 2012

Authors

Affiliations

F. FRANK ZBORALSKE, M.D.
From the Departments of Radiology, Pharmacy, and Pathology, University of California, San Francisco Medical Center, San Francisco, California
PHILLIP A. HARRIS, PHARM.D.
From the Departments of Radiology, Pharmacy, and Pathology, University of California, San Francisco Medical Center, San Francisco, California
SIDNEY RIEGELMAN, PH.D.
From the Departments of Radiology, Pharmacy, and Pathology, University of California, San Francisco Medical Center, San Francisco, California
OSCAR N. RAMBO, M.D.
From the Departments of Radiology, Pharmacy, and Pathology, University of California, San Francisco Medical Center, San Francisco, California
ALEXANDER R. MARGULIS, M.D.
From the Departments of Radiology, Pharmacy, and Pathology, University of California, San Francisco Medical Center, San Francisco, California

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